fig2

Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia

Figure 2. Prevention of stress-induced ventricular tachycardia in R176Q/+ mice at 6 weeks after AAV9. (A) Representative surface ECG (top) and intracardiac ventricular (V) lead (bottom) during programmed electrical stimulation (middle part of tracing). (B) Incidence of ventricular tachycardia induction in WT (n = 7 mice), RQ control (Con) (n = 8 mice), and RQ gRNA-SaCas9 (n = 7 mice) groups. The Fisher exact test was performed to compare for differences in arrhythmia induction (B).

The Journal of Cardiovascular Aging

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