fig2

Figure 2. Tnni3^R186Q/R186Q mice exhibit aberrant fatty acid metabolism. (A) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of differentially expressed genes in Tnni3^+/+ and Tnni3^R186Q/R186Q mice ventricular myocardium (n = 3 per group). (B) Lipogenesis in the ventricular myocardium from Tnni3^+/+ and Tnni3^R186Q/R186Q mice was determined by Oil Red O staining using frozen sections (n = 3 per group). (C-E) The levels of TG, TC and LDL were individually measured using enzyme-linked immunosorbent assay in the ventricular myocardium of Tnni3^+/+ and Tnni3^R186Q/R186Q mice (n = 3 per group). (F-H) The levels of TG, TC and LDL were individually measured using enzyme-linked immunosorbent assay in the serum of fasting Tnni3^+/+ and Tnni3^R186Q/R186Q mice (n = 3 per group). *P < 0.05,***P < 0.001 and ns: not significant. The statistical test was performed with an unpaired T-test.