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From: Deletion of the Lmna gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretory phenotype

Deletion of the <i>Lmna </i>gene in fibroblasts causes senescence-associated dilated cardiomyopathy by activating the double-stranded DNA damage response and induction of senescence-associated secretory phenotype

Figure 4. Electrocardiographic recordings. Two-channel cardiac rhythm recordings are shown in the WT, Pdgfra-Cre, Pdgfra-Cre:Lmna^W/F, and Pdgfra-Cre:Lmna^F/F mice. The Pdgfra-Cre:Lmna^W/F mice showed second and third-degree atrioventricular blocks after one year of age (third set of panels). The Pdgfra-Cre:Lmna^F/F mice exhibited runs of wide complex and narrow complex tachycardia episodes at 6 weeks of age (the lower panels).

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Committee on Publication Ethics

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Committee on Publication Ethics

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