fig9

Figure 9. Effect of suppression or activation of the β-catenin in the postmitotic cardiac myocytes on myocardial apoptosis at 4 weeks of age. (A) Representative images of Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) stained thin myocardial sections at 4 weeks of age in WT, Myh6-Mcm, Myh6-Mcm:Ctnnb1^LoF, and Myh6-Mcm:Ctnnb1^GoF hearts showing no difference in the number of TUNEL-stained cells. (B) Quantitative data showing the number of TUNEL-positive nuclei in the WT, Myh6-Mcm, Myh6-Mcm:Ctnnb1^LoF, and Myh6-Mcm:Ctnnb1^GoF hearts (n = 5). (C) RT-PCR data showing transcript levels of genes involved in regulating myocardial apoptosis in the four experimental groups (n = 4-5). WT: Wild type; Myh6-Mcm: myosin heavy chain 6-MerCreMer; RT-PCR: reverse transcription-polymerase chain reaction.