fig2
Figure 2. RNA-sequencing data depicting genotype-dependent clustering of cWNT/β-catenin activation or suppression in the cardiac myocytes. (A) Principal component analysis of cardiac myocyte transcriptome obtained through RNA-Seq data of wild type, β-catenin GoF and LoF showing distinct genotype-dependent segregation. (B) Correlation map of cardiac myocyte transcriptome in wild type, Myh6-Mcm:Ctnnb1LoF and Myh6-Mcm:Ctnnb1GoF hearts depicting strong correlation among the samples. Myh6-Mcm: Myosin heavy chain 6-MerCreMer; RNA-Seq: RNA-Sequencing; GoF: gain-of-function; LoF: loss-of-function.
