fig5

Systemic delivery of large-scale manufactured Wharton's Jelly mesenchymal stem cell-derived extracellular vesicles improves cardiac function after myocardial infarction

Figure 5. Echocardiography measurements of cardiac function parameters. (A) Ejection fraction percentage at each time point. (B) Cardiac output at each time point. (C) Stroke volume at each time point. (D) Fractional shortening at each time point. Baseline n = 10-13 in all groups, week 1, 4, and 8 n = 14. **P < 0.01, ***P < 0.001, +P < 0.05. EF: Ejection fraction; WJMSC: Wharton’s Jelly-derived mesenchymal stem cell; EV: extracellular vesicle; PLT: human platelet lysate; FBS: fetal bovine serum.

The Journal of Cardiovascular Aging

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