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Cardiovascular Aging



  • Yibin Wang, Ph.D.

    Professor and Director, Signature Program in Cardiovascular and Metabolic Diseases, Duke-NUS Medical School; Senior Principal Investigator and Co-Director, Singhealth Duke-NUS National Heart Research Institute Singapore (NHRIS), National Heart Centre Singapore, Singapore.


  • David A. Kass, M.D.

    Abraham and Virginia Weiss Professor of Cardiology; Professor of Biomedical Engineering; Professor of Pharmacology and Molecular Sciences; Director, Institute of CardioScience; Johns Hopkins University School of Medicine, Baltimore, MD, USA.

    Dr. David Kass is an eminent physician-scientist who has made seminal contributions to the molecular basis of cardiac function and heart failure. Utilizing an integrated approach involving a broad array of disciplines ranging from basic molecular biology to biomedical engineering, Dr. Kass has advanced his seminal discoveries to the conduct of randomized clinical trials and the care of patients with heart failure.

    Dr. Kass graduated Suma Cum Laude from Harvard University in Applied Physiology and Engineering and received his M.D. from Yale University in 1975. Dr. Kass completed his internal medicine residency at George Washington University and cardiology fellowship training at Johns Hopkins University. Upon completion of his training, Dr. Kass joined the faculty at Johns Hopkins University in 1986 and rose to the academic rank of full professor. He has held the endowed position of Abraham and Virginia Weiss Professor of Cardiology since 2004 and Professor of Medicine, Pharmacology, Molecular Sciences, and Biomedical Engineering. Dr. Kass is also the Director of research at the Division of Cardiology and Institute of CardioScience.

    Dr. Kass has made seminal contributions to cardiovascular sciences and has pioneered the application of pressure-volume analysis and ventricular-arterial coupling to the understanding of heart failure in humans. Likewise, Dr. Kass has pioneered human studies of cardiac resynchronization therapy. At the basic mechanistic level, Dr. Kass's trailblazing research has delineated several mechanisms involved in the regulation of cardiac muscle contraction and relaxation, including the role of nitroxyl and protein kinase G activation in heart failure.

    Dr. Kass has published his seminal findings in over 500 articles, which have garnered over 40,000 citations on the Web of Science (Clarivate) and have earned him an H index of 111 (Google Scholar H index 146). Several notable publications have received over 1,000 citations.

    In recognition of his scientific contributions, Dr. Kass has been awarded the Distinguished Scientist Award from the American Heart Association, the Innovator Award from the International Society of Heart Research, the Louis and Artur Lucien Prize in Cardiovascular Diseases and the Outstanding Investigator Award from NHLBI, among many others.

    Dr. Kass is also an outstanding mentor and has trained over 100 physicians and scientists many of whom have become established scientific leaders.

    The lectureship is named after Kiichi Sagawa, M.D., Ph.D. a pioneer in cardiac hemodynamics and professor of biomedical engineering at the John Hopkins University School of Medicine.

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