fig9

Mutant SRF and YAP synthetic modified mRNAs drive cardiomyocyte nuclear replication

Figure 9. SRF153(A3) and YAP5SA mmRNA treated cardiomyocytes induced chromatin accessibility. (A) Principal component analysis (PCA) plot of ATAC-seq data. (B) Heat map showing genome-wide chromatin accessibility using the read depth. (C) Heat maps of ATAC-seq signal intensity of the genes involved in DNA replication (GO:0006260), nuclear division (GO: 0000280), and positive regulation of cell cycle (GO:0045787). (D) Gene ontology analysis in terms of biological processes on the combination of unique peaks.

The Journal of Cardiovascular Aging

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/

Portico

All published articles are preserved here permanently:

https://www.portico.org/publishers/oae/