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From:  Mutant SRF and YAP synthetic modified mRNAs drive cardiomyocyte nuclear replication
Mutant SRF and YAP synthetic modified mRNAs drive cardiomyocyte nuclear replication

Figure 8. Cardiomyocytes transfected with a combination of SRF153(A3) and YAP5SA mmRNA mutants induced DNA replication and replisome genes. (A) Heat map of DNA replication and replisome genes at 32 h post-transfection between combination treatment group and control group. (B) Model of the core eukaryotic DNA replication. Upregulated genes under SRF153(A3) and YAP5SA combination treatment are shown in red.

The Journal of Cardiovascular Aging
ISSN 2768-5993 (Online)
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